Lia di Gregorio— I've never seen this before, pearls on the inside of a piece, next to the wearer's skin. It's super sensuous (have you ever run your fingers over pearls?). I also love this because another gripe I have about women's fashion is that garments made with really beautiful, tactile fabrics like silk and velvet are so often completely underwhelming in terms of skinfeel for the wearer—the soft side is facing out for the viewer, and unless the silk (for instance) is sueded or double-faced, the wearer gets nearly nothing. (Maybe I would actually call this jewelry feminist if it weren't thousands of dollars per piece!) The necklace with floating rubies similarly looks like it has the quality of soft thread, that it would be gentle and airy to wear.
There also might be something to the fact that pearls are way more delicate and soft than other gems. I have to imagine that putting them against the skin like that will wear down the nacre, especially on something that has heavy movement like a ring. Maybe this is slyly intentional on the part of di Gregorio, or maybe it just doesn't matter to someone buying a $4,000 ring that they'll have to replace the pearl in 8 years.